Is Clobetasol a glucocorticoids?
Clobetasol propionate is a corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis. Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.
What is the mechanism of action for Clobetasol?
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.
What class of drug is Clobetasol?
Clobetasol is in a class of medications called corticosteroids. It works by activating natural substances in the skin to reduce swelling, redness, and itching.
Is clobetasol propionate water soluble?
NONPROPRIETARY NAME : Clobetasol Propionate Topical Solution, USP 6. 15. CHEMICAL NAME STRUCTURE AND PHYSICAL PROPERTIES: Clobetasol Propionate is a white cream-colored crystalline powder insoluble in water.
What does clobetasol treat?
Clobetasol propionate is a medicine that’s used on the skin to treat swelling, itching and irritation. It can help with skin problems such as: eczema, including contact dermatitis. psoriasis.
What are the side effects of clobetasol propionate?
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- Burning sensation of the skin.
- dry skin.
- flushing or redness of the skin.
- itching, scaling, severe redness, soreness, or swelling of the skin.
- skin irritation.
- skin rash, encrusted, scaly and oozing.
How long does it take clobetasol to absorb into skin?
by Drugs.com It takes about one to three days for clobetasol propionate to start working when it is being used to treat eczema. Some improvement in symptoms such as inflammation (redness) and itching, should be noticed within this time.
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