Who created Pneumovax 23?
Manufacturer: Merck Sharp & Dohme Corp.
Who created the pneumonia vaccine?
Sir Almroth Wright coordinated the first trial of a whole-cell pneumococcal vaccine in South Africa from 1911 to 1912.
How is Pneumovax 23 made?
PNEUMOVAX 23 (Pneumococcal Vaccine Polyvalent) is a sterile, liquid vaccine consisting of a mixture of purified capsular polysaccharides from Streptococcus pneumoniae types (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F). PNEUMOVAX 23 is a clear, colorless solution.
When did pneumococcal polysaccharide come out?
Pneumococcal Vaccines The first pneumococcal polysaccharide vaccine was licensed for use in the United States in 1977. It contained purified capsular polysaccharide antigen from 14 different types of pneumococci.
What is the difference between Pneumovax and Prevnar?
The main difference between Pneumovax 23 and Prevnar 13 is how many different types of bacteria they target. Pneumovax 23 protects against 23 types of pneumococcal bacteria and is used in adults, while Prevnar 13 protects against 13 types of pneumococcal bacteria, and was designed primarily for children.
What is the pneumonia vaccine composed of?
Types and Composition of Pneumococcal Vaccines PCV13 (Prevnar13®) includes purified capsular polysaccharide of 13 serotypes of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 18C, and 23F) conjugated to a nontoxic variant of diphtheria toxin known as CRM197.
When was pneumococcal vaccine introduced India?
However, in mid 2010, a new 13-valent conjugate vaccine (PCV13) was launched in India. PCV 13 has replaced PCV 7 world over, including India..
What are the ingredients of Pneumovax 23?
The 23 types of pneumococcal polysaccharide in the vaccine are types 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F and 33F. Other ingredients – phenol, sodium chloride and water for injections.
What are the ingredients in Pneumovax?
The vaccine contains 0.02% polysorbate 80, 0.125 milligrams of aluminum as aluminum phosphate adjuvant, and 5 mL of succinate buffer. The vaccine does not contain thimerosal preservative. Pneumococcal polysaccharide vaccine (PPSV23 or Pneumovax23®) includes purified preparations of pneumococcal capsular polysaccharide.
Which is a polysaccharide vaccine?
Polysaccharide vaccines (meningococcal, pneumococcal, and typhoid) are poorly immunogenic and therefore less effective in children <2 years old.