What is the HBV serological marker determined during this stage?
HBsAg is the serological hallmark of HBV infection. After an acute exposure to HBV, HBsAg appears in serum within 1 to 10 weeks. Persistence of this marker for more than 6 months implies chronic HBV infection (8).
What are the indicators of serological tests of HBV infection?
Along with HBsAg, the serologic markers typically used to differentiate between acute, resolving, and chronic infection are anti-HBs, IgM, and total anti-HBc. Acute hepatitis B is characterized by the presence of HBsAg, positive IgM anti-HBc, and elevated transaminase levels (ie, 1000-2000 IU/mL).
What is the first serological marker of HBV infection?
HBsAg (hepatitis B surface antigen) is the first serologic marker to appear in a new acute infection, which can be detected as early as 1 week and as late as 9 weeks, with an average of one month after exposure to the hepatitis B virus (HBV).
What serologic pattern is most likely to be observed in incubation period of hepatitis B infection?
Anti‐HBc IgM (hepatitis B core antibody) is observed during acute infection.
What is serology test for hepatitis B?
The diagnostic panel for hepatitis B serology – allowing determination of susceptibility, active infection, or immunity through vaccination or past infection – includes testing for: hepatitis B surface antigen (HBsAg) hepatitis B surface antibody (anti-HBs) hepatitis B core antibody (anti-HBc) (Table 1).
How do you test for hepatitis B infection?
Blood tests. Blood tests can detect signs of the hepatitis B virus in your body and tell your doctor whether it’s acute or chronic. A simple blood test can also determine if you’re immune to the condition.
What is HBc IgM?
IgM antibody to hepatitis B core antigen (IgM anti-HBc): Positivity indicates recent infection with hepatitis B virus (<6 mos). Its presence indicates acute infection.
What is pre Icteric phase?
Prodromal (pre-icteric) phase: Nonspecific symptoms occur; they include profound anorexia, malaise, nausea and vomiting, a newly developed distaste for cigarettes (in smokers), and often fever or right upper quadrant abdominal pain. Urticaria and arthralgias occasionally occur, especially in HBV infection.