What class of drug is Drotaverine?

What class of drug is Drotaverine?

Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth. It is structurally related to papaverine, is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects.

What group of drug is Drotin?

About DROTIN INJECTION DROTIN INJECTION belongs to a group of medicines called anti-spasmodic agents used to reduce and relieve muscle spasms in the gastrointestinal tract, urinary tract, and gall bladder.

What is Drotaverine hcl used for?

Drotaverine is used to alleviate gastrointestinal and genitourinary smooth muscle spasms, such as cholecystitis and gallbladder disorders. Drotaverine is an e spasmolytic agent with a relaxing effect on smooth muscles. It works to relieve visceral spasms and improve cervical dilation.

What is the mechanism of action of Drotaverine?

Drotaverine inhibits phosphodiesterase hydrolysing cAMP, thereby increasing cAMP concentration, decreasing Ca uptake of the cells and changing the distribution of calcium among the cells. It may also have minor allosteric calcium channel blocking properties. It is a smooth muscle relaxant.

Is Drotin a paracetamol?

DROTAVERINE+PARACETAMOL is a combination of two drugs: Drotaverine (antispasmodic) and Paracetamol (pain killer). Drotaverine works by relieving contractions (spasms) associated with smooth muscles of the abdomen. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer).

Can Drotaverine be given IM?

Drotaverine hydrochloride may be applied as an additional drug for hypertonic crises as well. The preparation is indicated for intramuscular, subcutaneous, intravenous injections.

Is Drotin safe for children?

Conclusion: Drotaverine hydrochloride is an effective and safe pharmaceutical agent in the management of recurrent abdominal pain in children.

What is the side effect of Drotaverine?

Drotaverine has some side effects like nausea, vomiting, dry mouth, dizziness, etc. These side effects are mild and may subside by themselves. Consult your doctor if they bother you or worsen. Do not take this medicine if you are allergic to it.

Is Drotin safe for kidney?

The most frequent side-effects were a transitory decrease in blood pressure, vertigo, nausea or vomiting. Conclusion: Intravenous drotaverine provides effective pain relief in more than two-thirds of patients with renal colic, with no serious side-effects.

Can Drotaverine be given to child?

Is Drotaverine hydrochloride an antibiotic?

Drotin Tablet is an anti-spasmodic medicine which relieves contractions (spasms) associated with smooth muscles in the abdomen.

Can I take Drotaverine and paracetamol together?

By blocking COX enzyme’s effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, DROTAVERINE+PARACETAMOL helps in relieving abdominal pain and cramps.