How do you give amikacin IV?
Amikacin injection comes as a liquid to be injected intravenously (into a vein) or intramuscularly (into a muscle) every 8 or 12 hours (two or three times a day). When amikacin is injected intravenously, it is usually infused (injected slowly) over a period of 30 to 60 minutes.
Is amikacin single use?
Use: Amikacin injection is used to treat susceptible gram-negative bacterial infections. Packaging: Package in sterile, tight, single-use containers. Labeling: For professional use only. Keep out of the reach of children.
What is amikacin IV used for?
Amikacin injection is used to treat serious bacterial infections in many different parts of the body. This medicine is for short-term use only (7 to 10 days). Amikacin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth.
How fast does amikacin?
At the recommended dosage level, uncomplicated infections due to amikacin-sensitive organisms should respond in 24 to 48 hours. If definite clinical response does not occur within 3 to 5 days, therapy should be stopped and the antibiotic susceptibility pattern of the invading organism should be rechecked.
Can amikacin be given subcutaneously?
Pharmacokinetics. Amikacin is well absorbed following intravenous, subcutaneous, or intramuscular injection but is not appreciably absorbed orally.
Is amikacin bactericidal or bacteriostatic?
The concentration dependence of amikacin bactericidal activity was confirmed for Escherichia coli and Enterobacter cloacae and, to a lesser extent, for Serratia marcescens and Pseudomonas aeruginosa.
How much Amikacin can you take for urinary tract infection?
When amikacin is indicated in uncomplicated urinary tract infections, a dose of 250 mg twice daily may be used. Intramuscular Administration for Patients with Impaired Renal Function-Whenever possible, serum amikacin concentrations should be monitored by appropriate assay procedures.
Can amikacin be given intramuscular?
Amikacin Sulfate Injection, USP may be given intramuscularly or intravenously. The status of renal function should be estimated by measurement of the serum creatinine concentration or calculation of the endogenous creatinine clearance rate. The blood urea nitrogen (BUN) is much less reliable for this purpose.
What is the dosage of amikacin for newborns?
When amikacin is indicated in newborns (see “WARNINGS” box), it is recommended that a loading dose of 10 mg/kg be administered initially to be followed with 7.5 mg/kg every 12 hours. The usual duration of treatment is 7 to 10 days.
How do you calculate dose on hand for weight-based IV drip?
5) Multiply by the drop set to get a Weight-based IV drip. VTBI (volume to be infused) x Drop Factor ÷ by concentration. ml X gtts/ml ÷ [concentration] = drip rate. “Dose on hand” refers to the total availability of the drug in each unit of distribution (bag, vial, etc).