Can you have lymphoma of the spleen?
Splenic marginal zone lymphoma (splenic MZL) is rare. It accounts for fewer than 2 in every 100 cases of non-Hodgkin lymphoma. Splenic MZL can affect people of any age but it is most common in people in their 60s. In most cases, it is not known what causes splenic MZL.
What is spleen lymphoma?
Splenic marginal zone lymphoma (SMZL) is a slow-growing (indolent) B-cell non-Hodgkin lymphoma (NHL). It usually affects the spleen, bone marrow and blood. It can sometimes affect lymph nodes in the abdomen, but in most cases SMZL doesn’t affect lymph nodes. SMZL is linked with viral infections, especially. hepatitis.
Why does the spleen enlarged with lymphoma?
This is usually because an enlarged spleen may remove too many blood cells. It can also happen if lymphoma cells build up in the bone marrow. These cells take up space, which makes it difficult for the bone marrow to make enough normal blood cells.
What does a CT scan of the spleen show?
A CT scan remains the most useful preoperative investigation to measure splenic volume; to exclude lymph nodes at the splenic hilum; and to detect accessory spleens, splenic abscesses, and perisplenitis.
What are the symptoms of lymphoma of the spleen?
What are the symptoms?
- enlarged spleen, which may become twice as large as normal.
- pain in the abdomen, usually in the upper left corner.
- weakness.
- unexplained weight loss.
- fatigue.
- fever.
- night sweats.
- high levels of lymphocytes in the blood.
Does your spleen swell with lymphoma?
Lymphoma and the spleen Lymphoma cells can build up inside your spleen, making it swell. Sometimes, this might be the only sign that you have lymphoma.
Does a CT scan show spleen problems?
Blood tests, such as a complete blood count to check the number of red blood cells, white blood cells and platelets in your system and liver function. Ultrasound or CT scan to help determine the size of your spleen and whether it’s crowding other organs. MRI to trace blood flow through the spleen.
Can a CT scan detect an enlarged spleen?
An x-ray, ultrasound, CT, or MRI may show the enlarged spleen. You may be given contrast liquid to help the spleen show up better in the pictures.
How long can you live with splenic lymphoma?
The median overall survival in most series is about ten years and 70% of the patients can remain treatment free for five years. 17, 36, 53 There is no survival benefit for the association of chemotherapy with splenectomy,17 although some studies report increases in overall response rates.
What are the symptoms of splenic lymphoma?
What is splenic lymphoma of the spleen?
Splenic lymphoma. Splenic lymphoma , also termed as lymphomatous involvement of the spleen, represents the most common malignancy to involve the spleen. They are commonly secondary, rarely being primary (referred as primary splenic lymphoma ). This article focuses on the location-specific primary and secondary lymphomas involving the spleen,…
Can imaging data be used to diagnose primary splenic lymphoma?
Materials and methods: Pathological and imaging data from 17 patients with primary splenic lymphoma initially diagnosed at splenectomy were retrospectively analyzed. Pretreatment computed tomography (CT) imaging was available for 16 patients, and magnetic resonance imaging (MRI) data were available for 4 patients.
Can splenic lymphoma be seen on pet?
PET has become the imaging modality of choice to stage and follow-up of Hodgkin and aggressive forms of NHL disease 4 . Splenic lymphoma can manifest on PET either as a diffusely FDG-avid spleen, in cases of a diffuse infiltrative disease, or as single or multiple FDG-avid focal splenic lesions 4 .
What is the prevalence of spleen lymphoma?
The spleen is involved in about 30% of all Hodgkin lymphoma and 30-40% of patients with systemic non-Hodgkin lymphoma (NHL) 2,4. The primary splenic lymphoma is rarer, representing about 2% of all lymphomas 2.