Can stem cells repair kidney damage?

Can stem cells repair kidney damage?

Stem cells have shown great potential in kidney injury repair and disease treatment, but some pressing issues remain to be resolved before the clinical application.

Who qualifies for autologous stem cell transplant?

Which patients are candidates for autologous stem cell transplantation? Usually, ASCT is indicated for patients under 65 years of age with no severe comorbidities.

How long does it take to recover from an autologous stem cell transplant?

Recovery time depends on the type of transplant: Donated bone marrow or peripheral blood stem cell transplant can take 2-3 weeks. Cord blood engraftment can take 3-5 weeks. Self-donated stem cell transplant (autologous) takes about 10 days for recovery.

Is it possible to grow a kidney from stem cells?

For patients with kidney failure, the ability to replace a damaged kidney with a healthy kidney grown from their own cells could be a life saver. Fortunately, stem cell technologies have advanced profoundly in recent years, and it is now possible grow a population of stem cells from just a small swab of skin cells.

What is the long-term outcome of autologous stem cell transplantation for ASCT?

In cases where kidney dysfunction persists after ASCT, a haematological response may permit successful kidney transplantation with improved graft viability and decreased risk of recurrence. Long-term outcome of autologous stem cell transplantation in light chain deposition disease

Does stem cell therapy have a future in the field of kidney?

Nevertheless, it appears that stem cell therapy will have a great future in the field of kidney regeneration. Further clarification will be gained on the stem cells’ protective mechanisms in the treatment of kidney diseases through further understanding of the mechanisms of stem cells’ actions in vivo.

Is stem cell transplantation an effective treatment for light chain deposition disease?

Long-term outcome of autologous stem cell transplantation in light chain deposition disease ASCT may be an effective therapy for renal dysfunction associated with LCDD.

How to generate endocrine effect from stem cell transplantation?

Other strategies were to transplant stem cells or stem cell-derived extracellular vesicles to generate paracrine effect/endocrine effect, and to use kidney organoid formation to replace whole kidney organ.